Discussion

Compound managers are challenged with the timely delivery of cherry-picked samples to their customers, while assuring that the delivered samples are of high quality. Additional effort is associated with monitoring the quality of samples contained in multiple copies of screening libraries themselves. This presentation will focus on the impact of the “Plate Auditor” platform on Scripps’ compound management and HTS operations. The Plate Auditor simultaneously measures sample volume, color and the presence of precipitate in plate-based samples. The impact of this instrument on Scripps’ QA/QC of cherry-picked samples will be presented, as well as the results of a comprehensive audit of ~1 million samples from Scripps’ screening libraries.