Mass cytometry is an adaptation of inductively-coupled plasma mass spectroscopy to single cell analysis. The technology enables massive multiparametric analysis of single cells to investigate cellular responses in heterogeneous populations. Cells are labeled with antibody probes that are coupled to transition elements and lanthanides. The presence and abundance of mass tags on individual cells is used to understand cell responses in such complex and heterogeneous populations as human lymphocytes.
This talk will introduce the technology, discuss strengths and shortcomings and describe it’s application within a drug discovery environment.
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