Authors
D M Karamanou1; D Pousios1; C Barlow1;
1 University Hospital Southampton
Objective
The Sorin Crown PRT valve is a new addition to the surgeons’ armamentarium of aortic valve bioprostheses. We sought to evaluate the early outcomes and haemodynamic parameters of this bovine stented bioprosthesis in consecutive patients undergoing aortic valve replacement (AVR). This is a single centre case series with comparison to the previous generation Sorin bovine bioprosthesis Mitroflow.
Methods
We undertook retrospective analysis of prospectively collected data in consecutive AVR patients with a Crown valve in a 7 month period between March and September 2015, with comparison to consecutive AVR patients from October 2014 to March 2015 performed with the Sorin Mitroflow valve. We analysed the haemodynamic parameters from transthoracic echocardiography performed prior to discharge from hospital. Statistical analysis was performed with an independent t test.
Results
Number of patients undergoing AVR with Crown versus Mitroflow respectively 55 vs 56. Mean age 77.3 vs 79.4 (p=0.18). Procedure profile: 49% isolated AVR vs 37.5% (p=0.25). Post-operative echocardiographic findings were: mean gradient 13.2mmHg vs 12.9mm Hg (p=0.81), indexed effective orifice area 0.78 vs 0.77 (p=0.88), DVI 0.47 vs 0.46 (p=0.8). The clinical outcomes included: 0% mortality and 0% paravalvular leaks for both groups, stroke 5.4% vs 5.3% (p=1), permanent pacemaker 1.8% in both groups (p=1).
Conclusion
Surgical AVR can be safely performed with this new stented bioprosthesis with good haemodynamic results. In our case series we have demonstrated excellent clinical outcomes with good post operative haemodynamics which compare favourably with an established low haemodynamic profile valve.