Drug Discovery 2019 - Looking back to the future
Poster
200

Graphene-Biosensor for handheld biomolecular interaction analysis device

Authors

R Wang2; L Vasadi2; B Darroch1; C von Bieberstein1; S Hofmann2
1 HexagonFab Biosensors, UK;  2 University of Cambridge, UK

Abstract

We have developed a sensor platform based on the atomically-thin nanomaterial ‘graphene’. Thanks to graphene’s exceptional properties, it is possible to offer lab-like sensitivity in a small, portable device at an affordable price. 
Using these single-layer nanomaterials, we have developed a handheld tool that can perform biomolecular interaction analysis for drug discovery. 

The graphene-channel is sensitive to electric charges. When the analyte binds to the immobilised antibody on the surface, this changes the electric charge in the vicinity of the graphene. As a result, the resistance of the graphene-layer changes, which is the signal that our reader detects.

Programme

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ELRIG

The European Laboratory Research & Innovation Group Our Vision : To provide outstanding, leading edge knowledge to the life sciences community on an open access basis