Abstract

Plants
have a long history of use in medicine, with many important drugs being based
on chemicals identified or extracted from plants. However, the use of whole
plants as a source of therapeutic biologics has gained only modest traction
since the inception of ‘molecular pharming’. Molecular pharming turns an
individual plant into a miniature bioreactor capable of producing a wide range
of recombinant proteins.  Using a
proprietary transient expression technology, at Leaf Expression Systems, target protein is produced inside
the cells of whole plants in a highly scalable process with lower upstream
costs compared to traditional protein production technologies. Our protein
expression platform is proven in the production of a variety of biologics
covering therapeutic agents, vaccines and diagnostic tools. Scaling up is the
next step in the future of molecular pharming.