Abstract

Mechanistic MALDI MS-based cell assays, which measure single analytes in a cellular context, are successfully transitioning into industry. This talk will introduce participants to phenotypic MALDI MS cell. These acquire information on entire molecular signatures comprising arguably hundreds of molecules simultaneously. These can be analyzed using computational tools to reveal drug-response markers or responses biologically relevant stimuli. In addition, this talk will introduce to MALDI MS cell assays on droplet microarrays that utilize MALDI imaging MS as a readout.