Profile of Edgar Specker
Since 09/2009 Head of quality and compound management at the Screening Unit of the Leibniz Institute for Molecular Pharmacology (FMP), Berlin
09/2007 - 08/2009 Project leader at Jerini AG (now Shire Pharmaceuticals), Berlin, research cooperation with ALCON Research Ltd. for an ophthalmic indication
03/2006 - 07/2007 Medicinal chemist at N-Zyme BioTec GmbH (now Zedira GmbH),
Darmstadt, Project: synthesis of peptide based substrates and inhibitors for structure based drug design of transglutaminases
02/2005 - 02/2006 Movement of the group to Edinburgh: postdoctoral research fellow at the school of chemistry, University of Edinburgh, Scotland
06/2004 - 01/2005 Postdoctoral research fellow at the school of chemistry as a member of Prof. Bradley's research group, University of Southampton, England, Project: Screening of PNA conjugates encoding HIV
Protease substrate libraries based on DNA microrarray technology
11/2000 - 05/2004 Graduate Research assistant as a member of Prof. Klebe's research
group, Philipps university of Marburg, PhD thesis: De novo design and synthesis of novel lead structures as transition state isosteres for the selective inhibition of HIV protease and Cathepsin D