Pam Shaw

Biog:
Prof. Dame Pamela Shaw is a Clinician Scientist / Chair of Neurology at the University of Sheffield and Director of the Sheffield Institute for Translational Neuroscience (SITraN). Since 1991 she has led a multidisciplinary programme of research investigating genetic, molecular and neurochemical factors underlying motor neuron injury in ALS/MND and identifying and evaluating potential neuroprotective agents and improvements in symptomatic management in the clinic. Her current research focuses on the use of gene expression profiling in defined genetic subtypes of ALS to identify mechanisms of motor neuron injury, identify new therapeutic targets and indices of fast and slow disease progression using a variety of cellular and in vivo models and human biosamples.