Protein Sciences in Drug Discovery 2022

Wednesday 2 November
3 November
[Schedule with Sessions only]
All times shown are GMT —
DAY 1The Auditorium
DAY 2
08:00 08:00
08:05 08:05
08:10 08:10
08:15 08:15
08:20 08:20
08:25 08:25
08:30 Registration
08:30 (60 mins)
 08:30
08:35 08:35
08:40 08:40
08:45 08:45
08:50 08:50
08:55 08:55
09:00 09:00
09:05 09:05
09:10 09:10
09:15 09:15
09:20 09:20
09:25 09:25
09:30
Conference Welcome
Chairs: Lovisa Holmberg Schiavone, AstraZeneca  Theresia Schaedler, Maxion Therapeutics  Kate Smith, GlaxoSmithKline  
 09:30
09:35 09:35
09:40
High-throughput approaches for protein expression
Chairs: Hanna Tegel, Royal Institute of Technology (KTH)  Helena Firczuk, GSK  
Session Introduction
09:40 (5 mins)
Hanna Tegel, Royal Institute of Technology (KTH)  Helena Firczuk, GSK  
High-Throughput Protein Expression
09:45 (30 mins)
Nicola Burgess-Brown, Exact Sciences Innovation Ltd.  
Services and Tools for Protein Analysis: How Bio-Rad Can Boost Your Drug Discovery Workflow
10:15 (15 mins)
Richard Cuthbert — Bio-Rad    
 09:40
09:45 09:45
09:50 09:50
09:55 09:55
10:00 10:00
10:05 10:05
10:10 10:10
10:15 10:15
10:20 10:20
10:25 10:25
10:30 Refreshment Break 10:30
10:35 10:35
10:40 10:40
10:45 10:45
10:50 10:50
10:55 10:55
11:00 11:00
11:05 11:05
11:10 11:10
11:15
High-throughput approaches for protein expression
Chairs: Helena Firczuk, GSK  Hanna Tegel, Royal Institute of Technology (KTH)  
A high-throughput parallel protein workflow to accelerate antimicrobial drug discovery at LifeArc
11:15 (30 mins)
Peter Canning, LifeArc  
Automated assay for quantification of antibody titre in crude samples
11:45 (5 mins)
Ruizhi Wang — HexagonFab    
ASSIST Plus Pipetting Platform
11:50 (5 mins)
Kiran Sharma — INTEGRA Bioscience Ltd    
Accelerating Drug Discovery: A Refresh of the Lead Panel Generation Phase within Biopharm Discovery
11:55 (30 mins)
Edward Coulstock, GlaxoSmithKline  
Production of Cas9 orthologs for functional and structural studies
12:25 (15 mins)
Thomas Meins — WuXi AppTec    
 11:15
11:20 11:20
11:25 11:25
11:30 11:30
11:35 11:35
11:40 11:40
11:45 11:45
11:50 11:50
11:55 11:55
12:00 12:00
12:05 12:05
12:10 12:10
12:15 12:15
12:20 12:20
12:25 12:25
12:30 12:30
12:35 12:35
12:40 Refreshment Break with Poster Session 13.30 - 14.00 12:40
12:45 12:45
12:50 12:50
12:55 12:55
13:00 13:00
13:05 13:05
13:10 13:10
13:15 13:15
13:20 13:20
13:25 13:25
13:30 13:30
13:35 13:35
13:40 13:40
13:45 13:45
13:50 13:50
13:55 13:55
14:00
Advancement in protein production of novel and challenging soluble targets
Chairs: Panchali Goswami, GlaxoSmithKline  Valerie Pye, Francis Crick Institute  
Session Introduction
14:00 (5 mins)
Valerie Pye, Francis Crick Institute  Panchali Goswami, GlaxoSmithKline  
Investigating epigenetics using electron microscopy (and a little bit of Chemistry)
14:05 (30 mins)
Marcus Wilson, University of Edinburgh  
Enhance your separation power and increase product purity with the J.T.Baker® BAKERBOND® PROchievA™ protein A derived affinity chromatography resin
14:35 (5 mins)
Meera Pirie — Avantor    
 14:00
14:05 14:05
14:10 14:10
14:15 14:15
14:20 14:20
14:25 14:25
14:30 14:30
14:35 14:35
14:40
Poster Presentations
Poster Presentation Introductions
14:40 (5 mins)
Theresia Schaedler, Maxion Therapeutics  
‘SNARE Proteins’-Maximizing Protein Expression in Mammalian Cells.
14:45 (10 mins)
Angita Shrestha, GSK  
A novel screening platform to monitor GPCR-G proteins complex formation
14:55 (10 mins)
William Lee, AstraZeneca  
 14:40
14:45 14:45
14:50 14:50
14:55 14:55
15:00 15:00
15:05 Refreshment Break 15:05
15:10 15:10
15:15 15:15
15:20 15:20
15:25 15:25
15:30 15:30
15:35 15:35
15:40
Advancement in protein production of novel and challenging soluble targets
Chairs: Panchali Goswami, GlaxoSmithKline  Valerie Pye, Francis Crick Institute  
Exploiting the versatility of synthetic nanobodies in protein production and structural biology
15:40 (30 mins)
Lisa Joedicke, Roche  
Expression and Purification of a Challenging, Disordered Transcription Factor
16:10 (15 mins)
Duncan Smith — Peak Proteins Ltd    
Building the replisome: structure and mechanism of a DNA replication machine
16:25 (30 mins)
Joe Yeeles, MRC Laboratory of Molecular Biology  
 15:40
15:45 15:45
15:50 15:50
15:55 15:55
16:00 16:00
16:05 16:05
16:10 16:10
16:15 16:15
16:20 16:20
16:25 16:25
16:30 16:30
16:35 16:35
16:40 16:40
16:45 16:45
16:50 16:50
16:55
Keynote Presentation
Keynote Introduction
16:55 (5 mins)
Lovisa Holmberg Schiavone, AstraZeneca  
Protein design using deep learning
17:00 (45 mins)
David Baker, University of Washington  
 16:55
17:00 17:00
17:05 17:05
17:10 17:10
17:15 17:15
17:20 17:20
17:25 17:25
17:30 17:30
17:35 17:35
17:40 17:40
17:45
Networking with Poster Session 18.30 - 19.00
 17:45
17:50 17:50
17:55 17:55
18:00 18:00
18:05 18:05
18:10 18:10
18:15 18:15
18:20 18:20
18:25 18:25
18:30 18:30
18:35 18:35
18:40 18:40
18:45 18:45
18:50 18:50
18:55 18:55
19:00 19:00