| Sunday 19 November |
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| DAY 1 | Room 3A | Room 3B | Hall 1B | Hall 1C | Room 11B - Workshop | Careers Zone, Main Exhibition Hall |
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| 08:00 | Event Registration | Early Career Professional Welcome Early Career Professional Welcome 08:00 (45 mins) Lisa Stott, Sosei Heptares |
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| 08:45 | ELRIG - Opening Session ELRIG - Annual Review - Visons & Values 08:45 (10 mins) Melanie Leveridge, GSK ELRIG - Equality, Diversity & Inclusion Guiding Principals 08:55 (5 mins) Clare Viney, Vitae ELRIG - Lifetime Achievement Award - A Career In Drug Discovery 09:00 (20 mins) Steve Rees, AstraZeneca Innovation and Automation during a Pandemic 09:20 (50 mins) Rob Howes, DHSC |
Platinum Sponsorship Presentation |
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| 10:10 | Refreshment Break | 10:10 | |||||||
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| 10:50 | New Approaches in Infection Biology Chairs: David Pallin, CRL Adrian Goldman, U. Helsinki |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Chairs: Nikki Carter, Excalibur Healthcare Emily Adams, Liverpool School of Tropical Medicine and Mologic |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Chairs: Wesley Blackaby, Servier Oliver Rausch, Storm Therapeutics Ltd |
Alzheimer’s Research UK Chairs: John Isaac, Janssen Neuroscience David Reynolds, AstronauTx Ltd |
Workshop Gaining a career in industry: Learning tips and tricks from the inside 10:50 (60 mins) Allan Jordan, Sygnature Discovery |
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| 11:00 | New Approaches in Infection Biology Neuropilin-1 facilitates SARS-CoV2 cell entry and infectivity 11:00 (30 mins) Maria Anastasina, University of Helsinki Diverse neutralizing SARS-CoV-2 antibodies identified from large-scale synthetic phage libraries target rare epitopes and retain binding to variants of concern. 11:30 (30 mins) Tom Yuan — Twist Bioscience |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Q-POCTM, a paradigm shift in rapid multiplex molecular diagnostics 11:00 (30 mins) Jonathan OHalloran, QuantumDx Transforming Drug Discovery Through Precision Research 11:30 (30 mins) Stephen Hague — 10x Genomics |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Discovery of risdiplam (evrysdi) - A medicine for the treatment of spinal muscular atrophy 11:00 (30 mins) Hasane Ratni , F. Hoffmam-La Roche A Fully Automated Data Analysis Workflow for Gene Expression-Based Screening 11:30 (30 mins) Gabriela Nass Kovacs — Genedata AG |
Alzheimer’s Research UK Alzheimer’s Research UK and its support for translational research. 11:00 (30 mins) Sara Imarisio, ARUK Coding cells for health: building translational disease models for drug discovery and therapeutics 11:30 (30 mins) Sara Gomes — bit.bio Marta Rucka — bit.bio |
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| 12:00 | New Approaches in Infection Biology Functional analysis of Bartonella pathogenicity factors might contribute to novel therapeutic concepts 12:00 (30 mins) Volkhard Kempf , Goethe University of Frankfurt am Main |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd A luminescent reporter cell line for authentic SARS-CoV-2 infection and neutralising antibody activity 12:00 (30 mins) Nick Matheson, University of Cambridge |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA mRNA Lightning platform for the discovery of selective small molecule mRNA regulatory drugs 12:00 (30 mins) Iris Alroy, Anima Biotech |
Alzheimer’s Research UK Identification of tool compounds targeting the SRSF1-dependent nuclear export of pathological C9ORF72-repeat transcripts 12:00 (30 mins) Lianne Van Beek, CRL Tennore Ramesh, Sheffield Institute for Translational Neuroscience (SITraN) |
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| 12:30 | Refreshment Break | Workshop Chairs: Lilian Hunt, EDIS, Wellcome Trust Inclusive research and experimental design 12:30 (60 mins) Lilian Hunt, EDIS, Wellcome Trust |
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| 14:00 | New Approaches in Infection Biology Targeting the human RED-SMU1 splicing complex as a basis for host-directed anti-influenza therapy 14:00 (30 mins) Nadia Naffakh, Institut Pasteur, CNRS Introducing TRFID, a UK-leading BSL3 translation biology facility for Infectious Diseases at Alderley Park 14:30 (5 mins) Helen Bright — Medicines Discovery Catapult LabLogic Life Sciences range has something for everyone 14:35 (5 mins) Lucy Farmer — LabLogic Systems Limited FidaBio: Characterizing Biomolecular behaviour by measuring and monitoring changes in hydrodynamic radius 14:40 (5 mins) Jo Walter — Fida Biosystems ApS |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Diagnostics for epidemics, pandemics and neglected tropical disease 14:00 (30 mins) Emily Adams, Liverpool School of Tropical Medicine and Mologic Mesoporous silica & PLGA nanoparticles for next-generation drug delivery & targeted therapeutic technologies 14:30 (5 mins) Philippe Saint-Cricq-Riviere — nanoComposix Assist Plus 14:35 (5 mins) Sharon Barnard — INTEGRA Biosciences |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Dynamic RNAs and Structure-Guided Small Molecule Drug Discovery 14:00 (30 mins) Isaac Kimsey, Nymirum Yang Zheng, Nymirum DNA-Encoded Library Technology for Drug Discovery 14:30 (5 mins) Assunta Romano — Merck Life Science |
Alzheimer’s Research UK Small molecule inhibitors of carboxylesterase Notum to potentiate Wnt signalling 14:00 (30 mins) Nicky Willis, UCL DDI Quantifying Morphological Change Using Label-Free Live-Cell Analysis 14:30 (15 mins) Jasmine Trigg — Sartorius |
Workshop Chairs: Anita Ramanathan, Word Cortex Exceptional Science Presentations: How to Effectively Communicate the Value of Your Work 14:00 (45 mins) Anita Ramanathan, Word Cortex |
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| 14:35 | Tecan UK Ltd |
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| 14:40 | Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Integrated Drug Discovery: Chemistry and Biology working together to create innovative solutions 14:40 (5 mins) Catherine Stace — Domainex |
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| 14:45 | New Approaches in Infection Biology Studies of the membrane-bound pyrophosphatase as a potential drug target against protist parasites 14:45 (30 mins) Keni Vidilaseris, University of Helsinki |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd EMERGING DIAGNOSTIC TECHNOLOGIES IN CLINICAL MICROBIOLOGY 14:45 (30 mins) Alex Van Belkum, Biomeirieux |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Small activating RNAs from concept to Phase 2 clinical trial 14:45 (30 mins) Vikash Reebye Nagy Habib , MiNA Therapeutics |
Alzheimer’s Research UK Development of eIF2B modulators for the treatment of neurodegenerative disease 14:45 (30 mins) Duncan Scott, Alborada Drug Discovery Institute, Cambridge |
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| 15:15 | Refreshment Break | 15:15 | |||||||
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| 15:45 | New Approaches in Infection Biology Developing inhibitors that block adhesin-collagen interactions 15:45 (30 mins) Dirk Linke, University of Oslo PerkinElmer’s Tools to study virus-host interaction and virus inhibition 16:15 (15 mins) Louise Affleck — PerkinElmer |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd Computer literate? Novel AI based reading of lateral flow devices 15:45 (30 mins) Daniel Wise, Excalibur Healthcare Design your molecular-based assays with confidence: Using ATCC’s Genome Portal bioinformatics platform to select wide-ranging, sequence-verified materials 16:15 (5 mins) Rebecca Charlton — LGC - ATCC Don't Let the Antibody be a Variable in Your Assay 16:20 (5 mins) Mark Twigden — Cell Signaling Technology Introducing Cytek cFluorTM Reagents and Assays 16:25 (5 mins) Michelle Jackson — Cytek Bio |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA Drugging RNA Modifying Enzymes – METTL3 Inhibitors as a novel therapeutic strategy for Acute Myeloid Leukemia 15:45 (30 mins) David Hardick, Storm Therapeutics Konstantinos Tzelepis , The Milner Therapeutics Institute |
Alzheimer’s Research UK Gene editing to treat expanded CAG/CTG repeat disorders 15:45 (30 mins) Vincent Dion, Cardiff Dementia Research Institute The new generation of live cell shipments 16:15 (5 mins) Simon Myrbäck — Cellbox Solutions High-Throughput Genome Editing for Disease Models 16:20 (5 mins) Nick Clare — Synthego Ulysses - Arctoris' end-to-end automation platform for accelerated drug discovery 16:25 (5 mins) Daniel Thomas — Arctoris Ltd |
Workshop How to select the best nanoparticle for next-gen drug delivery 15:45 (60 mins) Philippe Saint-Cricq-Riviere — nanoComposix |
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| 16:15 | Technology Spotlights |
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| 16:30 | New Approaches in Infection Biology Inhibition of bacterial virulence as an alternative to antibiotic treatment: Pseudomonas aeruginosa elastase as a target for antivirulence therapy 16:30 (30 mins) Martin Everett, Antabio |
Diagnostic Testing and Biomarkers - The New Normal? - sponsored by Ziath Ltd How to build a mobile lab for genomic surveillance of viral outbreaks 16:30 (30 mins) Joshua Quick, Institute of Microbiology and infection, University of Birmingham |
Innovations in Chemistry to Discover New Medicines: Approaches to Drugging RNA X-reactivation as an approach to treating Rett Syndrome 16:30 (30 mins) Jeannie Lee, Harvard |
Alzheimer’s Research UK Novel Therapeutic Targets for Treatment of Neurodegeneration 16:30 (30 mins) Paul Brennan, Oxford DDI |
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| 17:00 | Networking & Posters | 17:00 | |||||||
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