Translating Ideas into Therapies 2021- Co-hosted with the British Pharmacological Society

Targeting KRAS via inhibition of the KRAS-SOS1 interaction

Thu1  Jul11:10am(15 mins)
Where:
Conference Room
Speaker:
Sponsor:
NUVISAN
NUVISAN
Dr Roman Hillig

Abstract

Nuvisan provides fully integrated drug discovery and early development services. In this talk, we will highlight our capabilities and track record by presenting insights into a recent program targeting KRAS:
• Combination of high-throughput and fragment screening enabled a new approach to target KRAS,
• Guidance by intensive structural biology efforts and multiple biophysics approaches,
• Discovery of nanomolar, selective and cellularly active SOS1 inhibitors.
To view the video assoicated with this lecture click here
Youtube