Print
| Thursday 1 July |
| Conference Room | Workshop Room | DAY 2 |
| Conference Room | Workshop Room | DAY 2 | ||
| 09:00 | Welcome & Introductions Chairs: Katie Chapman, MSD Cherry Wainwright, Robert Gordon University |
09:00 | |||
| 09:05 | 09:05 | ||||
| 09:10 | Drugging your target Chairs: Katie Chapman, MSD Cherry Wainwright, Robert Gordon University Development of an Intracellular Quantitative Assay to Measure Compound Binding Kinetics 09:10 (20 mins) Charles Lay, University of Nottingham Accelerate functional genomics studies with simultaneous capture of CRISPR guides and gene expression profiles at single cell resolution. 09:30 (30 mins) Stephen Hague — 10x Genomics Potential use of CRISPR in therapeutic applications 10:00 (25 mins) Pinar Akcakaya, AstraZeneca |
09:10 | |||
| 09:15 | 09:15 | ||||
| 09:20 | 09:20 | ||||
| 09:25 | 09:25 | ||||
| 09:30 | 09:30 | ||||
| 09:35 | 09:35 | ||||
| 09:40 | 09:40 | ||||
| 09:45 | 09:45 | ||||
| 09:50 | 09:50 | ||||
| 09:55 | 09:55 | ||||
| 10:00 | 10:00 | ||||
| 10:05 | 10:05 | ||||
| 10:10 | 10:10 | ||||
| 10:15 | 10:15 | ||||
| 10:20 | 10:20 | ||||
| 10:25 | Refreshment Break | 10:25 | |||
| 10:30 | 10:30 | ||||
| 10:35 | 10:35 | ||||
| 10:40 | 10:40 | ||||
| 10:45 | Drugging your target Chairs: Katie Chapman, MSD Cherry Wainwright, Robert Gordon University The challenges of a novel target portfolio 10:45 (25 mins) Steve Rees, AstraZeneca Writing and erasing O-GlcNAc from target proteins in cells 11:25 (25 mins) Christina Woo, Harvard University Developing ligands for challenging targets by synthesizing and screening ten-thousands of macrocyclic compounds at a nanomole-scale 11:50 (25 mins) Christian Heinis, Ecole Polytechnique Fédérale de Lausanne (EPFL) |
10:45 | |||
| 10:50 | 10:50 | ||||
| 10:55 | 10:55 | ||||
| 11:00 | 11:00 | ||||
| 11:05 | 11:05 | ||||
| 11:10 | 11:10 | ||||
| 11:15 | 11:15 | ||||
| 11:20 | 11:20 | ||||
| 11:25 | 11:25 | ||||
| 11:30 | 11:30 | ||||
| 11:35 | 11:35 | ||||
| 11:40 | 11:40 | ||||
| 11:45 | 11:45 | ||||
| 11:50 | 11:50 | ||||
| 11:55 | 11:55 | ||||
| 12:00 | 12:00 | ||||
| 12:05 | 12:05 | ||||
| 12:10 | 12:10 | ||||
| 12:15 | Refreshment Break - please visit the Workshop Room for a 10xGenomic Hot Topic Discussion at 12.15 | 10x Genomics 10x Genomics Hot Topic Workshop Title Accelerate functional genomics studies with simultaneous capture of CRISPR guides and gene expression profiles at single cell resolution. Abstract: Pooled CRISP...[More] |
12:15 | ||
| 12:20 | 12:20 | ||||
| 12:25 | 12:25 | ||||
| 12:30 | 12:30 | ||||
| 12:35 | 12:35 | ||||
| 12:40 | 12:40 | ||||
| 12:45 | 12:45 | ||||
| 12:50 | 12:50 | ||||
| 12:55 | 12:55 | ||||
| 13:00 | 13:00 | ||||
| 13:05 | 13:05 | ||||
| 13:10 | 13:10 | ||||
| 13:15 | 13:15 | ||||
| 13:20 | 13:20 | ||||
| 13:25 | 13:25 | ||||
| 13:30 | 13:30 | ||||
| 13:35 | 13:35 | ||||
| 13:40 | 13:40 | ||||
| 13:45 | Clinical Insights & Experimental Medicine Chairs: Simon Chell, AstraZeneca Ajay Gupta Session Chair Welcome 13:45 (5 mins) Simon Chell, AstraZeneca Ajay Gupta Hepato-biliary organoids and applications in regenerative medicine 13:50 (25 mins) Monique Verstegen, Erasmus MC The consequenses of inaccurate or inappropriate cell analysis for down-stream assays 14:15 (15 mins) Suzanne Riches — Nexcelom from PerkinElmer Leveraging genetic insight into potential drug targets for vascular disease 14:30 (25 mins) Scott Damrauer, University of Pennsylvania |
13:45 | |||
| 13:50 | 13:50 | ||||
| 13:55 | 13:55 | ||||
| 14:00 | 14:00 | ||||
| 14:05 | 14:05 | ||||
| 14:10 | 14:10 | ||||
| 14:15 | 14:15 | ||||
| 14:20 | 14:20 | ||||
| 14:25 | 14:25 | ||||
| 14:30 | 14:30 | ||||
| 14:35 | 14:35 | ||||
| 14:40 | 14:40 | ||||
| 14:45 | 14:45 | ||||
| 14:50 | 14:50 | ||||
| 14:55 | Refreshment Break | 14:55 | |||
| 15:00 | 15:00 | ||||
| 15:05 | Clinical Insights & Experimental Medicine Chairs: Simon Chell, AstraZeneca Ajay Gupta Targeting SET-PP2A complex as a new avenue for therapeutic targeting of KMT2A-driven acute leukemia 15:05 (20 mins) Maria Teresa Esposito, University of Roehampton The TRAIL less travelled: targeting the pro-tumourigenic role of TRAIL in cancer 15:25 (25 mins) Henning Walczak, UCL |
15:05 | |||
| 15:10 | 15:10 | ||||
| 15:15 | 15:15 | ||||
| 15:20 | 15:20 | ||||
| 15:25 | 15:25 | ||||
| 15:30 | 15:30 | ||||
| 15:35 | 15:35 | ||||
| 15:40 | 15:40 | ||||
| 15:45 | 15:45 | ||||
| 15:50 | Refreshment Break | 15:50 | |||
| 15:55 | 15:55 | ||||
| 16:00 | The Many Facets of Prostacyclin Mimetics: Therapeutic Applications in Cardiovascular Disease 16:00 (50 mins) Keynote Speaker: Lucie Clapp, Institute of Cardiovascular Science, University College London |
16:00 | |||
| 16:05 | 16:05 | ||||
| 16:10 | 16:10 | ||||
| 16:15 | 16:15 | ||||
| 16:20 | 16:20 | ||||
| 16:25 | 16:25 | ||||
| 16:30 | 16:30 | ||||
| 16:35 | 16:35 | ||||
| 16:40 | 16:40 | ||||
| 16:45 | 16:45 | ||||
| 16:50 | 16:50 | ||||
| 16:55 | 16:55 | ||||
| 17:00 | 17:00 | ||||
| 17:05 | 17:05 | ||||
| 17:10 | 17:10 | ||||
| 17:15 | 17:15 | ||||
| 17:20 | 17:20 | ||||
| 17:25 | 17:25 | ||||
| 17:30 | 17:30 | ||||
| 17:35 | 17:35 | ||||
| 17:40 | 17:40 | ||||
| 17:45 | 17:45 | ||||
| 17:50 | 17:50 | ||||
| 17:55 | 17:55 | ||||
| 18:00 | 18:00 |