CRISPR in Drug Discovery 2021

Presentation

Tuesday 23 March

24 March

DAY 1

Conference Hall

DAY 2

All times shown are GMT —

DAY 1

Conference Hall

DAY 2

11:00

Welcome & Introductions

Welcome & Introductions
11:00 (5 mins)
Andrew Bassett, Wellcome Sanger Institute Klio Maratou, GlaxoSmithKline Marcello Maresca, AstraZeneca

11:00

11:05

Functional Genomics

Chairs: Andrew Bassett, Wellcome Sanger Institute

Functional Genomics to Guide Cancer Drug Discovery
11:05 (45 mins)
Mathew Garnett, Wellcome Sanger Institute

CRISPR screening to identify new drug targets in complex cell models
11:50 (30 mins)
Carlos le Sage — Horizon Discovery

11:05

11:10

11:15

11:20

11:25

11:30

11:35

11:40

11:45

11:50

11:55

12:00

12:05

12:10

12:15

12:20

Refreshment Break/Poster Session/Vendor Exhibition

12:20

12:25

12:30

12:35

12:40

12:45

12:50

12:55

13:00

13:05

13:10

13:15

13:20

Functional Genomics

Chairs: Andrew Bassett, Wellcome Sanger Institute

Session Chair Welcome
13:20 (5 mins)
Andrew Bassett, Wellcome Sanger Institute

Using CRISPR/Cas9 screens to study epidermal keratinocyte differentiation and inflammation
13:25 (20 mins)
Christopher Bryant, Wellcome Sanger Institute

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles
13:45 (20 mins)
Ulrich Elling, Institute of Molecular Biotechnology, IMBA, Vienna

Joint Q&A Session
14:05 (20 mins)
Mathew Garnett, Wellcome Sanger Institute Christopher Bryant, Wellcome Sanger Institute Ulrich Elling, Institute of Molecular Biotechnology, IMBA, Vienna

FirePlex Multiplexed Assay Technology – a Cell-line Profiling Tool
14:25 (15 mins)
Zeev Gechtman — Abcam

13:20

13:25

13:30

13:35

13:40

13:45

13:50

13:55

14:00

14:05

14:10

14:15

14:20

14:25

14:30

14:35

14:40

Refreshment Break

14:40

14:45

14:50

14:55

15:00

Functional Genomics

Chairs: Marcello Maresca, AstraZeneca

Screening for functional transcriptional and splicing regulatory variants with GenIE
15:00 (20 mins)
Sarah Cooper , Wellcome Sanger Institute

CRISPR/Cas9 - from functional genomics applications to therapeutic genome editing
15:20 (20 mins)
Lars Steinmetz, EMBL

CRISPR Tools to Mitigate Attrition Rate Risk in Drug Development
15:40 (15 mins)
Kai Wilkens — Synthego

Accelerate functional genomics studies with simultaneous capture of CRISPR guides and gene expression profiles at single cell resolution.
15:55 (5 mins)
Stephen Hague — 10x Genomics

15:00

15:05

15:10

15:15

15:20

15:25

15:30

15:35

15:40

15:45

15:50

15:55

16:00

Refreshment Break

16:00

16:05

16:10

16:15

Functional Genomics

Chairs: Marcello Maresca, AstraZeneca

Ultra-high throughput single-cell RNA sequencing and perturbation screening by combinatorial fluidic indexing
16:15 (20 mins)
Paul Datlinger, CeMM Research Center for Molecular Medicine, Vienna

A single-cell CRISPR screen in >100k primary human T cells
16:35 (5 mins)
Tilmann Buerckstuemmer — Aelian Biotechnology

Advanced iPSC technologies for neurodegenerative disease research
16:40 (20 mins)
Michael Ward, NIH/NINDS

Joint Q&A Session
17:00 (20 mins)
Sarah Cooper , Wellcome Sanger Institute Lars Steinmetz, EMBL Paul Datlinger, CeMM Research Center for Molecular Medicine, Vienna Michael Ward, NIH/NINDS

16:15

16:20

16:25

16:30

16:35

16:40

16:45

16:50

16:55

17:00

17:05

17:10

17:15

17:20

Horizon Discovery
Hot Topic Discussion - Understanding the paradigm of cellular visualization...[More]

2021-03-23 17:20:002021-03-23 18:20:00Europe/LondonHorizon DiscoverySession at CRISPR in Drug Discovery 2021 https://www.myeventflo.com/eventflo.asp?evID=2348OnlineKlebo Admin, Klebo (Eventflo) Conference Platforminfo@elrig.org

17:20

17:25

17:30

17:35

17:40

17:45

17:50

17:55

18:00

18:05

18:10

18:15

18:20

18:25

18:30

18:35

18:40

18:45

18:50

18:55

19:00